What is HER2 Breast Cancer?

Posted on December 3, 2025 by Patrick Hercules

HER2-positive (HER2+) breast cancer is a fast-growing form of invasive breast cancer, one that spreads to other parts of the body. When a person has this type of cancer, tests show high levels of a specific protein, human growth factor receptor 2, which manages how cells grow and divide.

In 2023, the American Cancer Society estimated that invasive breast cancers would affect more than 290,000 women. Invasive breast cancers are cancers that have spread to the surrounding breast tissue. These cancers include:

· Invasive ductal carcinoma

· Lobular breast cancer

Additionally, of those 290,000 cases, between 15% and 20% of those breast cancers will be HER2-positive. Men rarely develop HER2-positive breast cancer.

Similar to many types of breast cancer, HER2-positive breast cancer may not cause obvious symptoms. When it does cause obvious symptoms, you may experience:

· A change in the size, shape, or contour of the breast

· A mass or lump, which may feel as small as a pea

· A lump or thickening in or near the breast or in the underarm that persists through a menstrual cycle

· A change in the look or feel of the skin of the breast. The skin may look dimpled, scaly, or inflamed, and may look reddish or darker than usual.

· A marble-like hardened area under the skin

· A blood-stained or clear fluid discharge from the nipple

HER2-positive breast cancer happens when the HER2 gene mutates, creating the HER2 protein. HER2 proteins or receptors are on all breast cells’ surfaces.

Normally, HER2 proteins manage breast cell growth and repair, making sure cells divide as needed to replace any cells that are damaged or dying. When HER2 genes mutate, they create more copies of themselves, which means more proteins that cause more breast cells to divide and grow and become cancerous tumors.

Many factors can increase the risk of developing HER2 breast cancer, including:

· Having an inherited genetic mutation, such as BRCA1 or BRCA2

· Having a personal history of breast cancer

· Having a condition such as atypical ductal hyperplasia

· Starting your menstrual cycle earlier than usual

· Starting menopause later than usual

· Taking hormone replacement therapy

· Having more than one alcoholic beverage in a day

· History of radiation therapy for conditions, including types of lymphoma

HER2-positive breast cancer causes many complications as it can spread or metastasize. About half of the people with it are diagnosed after the cancer has spread to other areas of the body, including the brain. Metastatic breast cancer in the brain can be life-threatening.

All breast cancers are diagnosed by healthcare providers when they perform breast biopsies. If the biopsies find cancer, a medical pathologist will examine breast tissue cells for signs of HER2 proteins. Laboratory tests can include:

· Immunohistochemistry

· Fluorescence in situ hybridization (FISH)

Since HER2-positive breast cancer is a form of invasive breast cancer, treatments will vary depending on factors such as cancer stage and HER2 status. Treatments may include:

· Targeted therapy

· Chemotherapy

If you would like to learn more about HER2-positive breast cancer, or to learn more about our cancer care program, you can schedule an appointment with an oncologist at our MediSys Health Network Cancer Center by calling (718) 206-6742.

All content of this newsletter is intended for general information purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Please consult a medical professional before adopting any of the suggestions on this page. You must never disregard professional medical advice or delay seeking medical treatment based upon any content of this newsletter. PROMPTLY CONSULT YOUR PHYSICIAN OR CALL 911 IF YOU BELIEVE YOU HAVE A MEDICAL EMERGENCY.

High Functioning Depression

Posted on December 2, 2025 by Xavia Malcolm

Depression is a mental health disorder characterized by a persistent feeling of sadness, hopelessness, or a loss of interest in things once enjoyed.

Depression affects approximately eight percent of adults living in the United States each year. Several of whom may experience debilitating symptoms that can affect their ability to keep up with the demands of day-to-day life.

While the symptoms of depression can present significant challenges for some individuals—affecting their work, relationships, and social lives—others may appear to cope successfully with their symptoms. The term “high-functioning depression” describes people who live with depression and seem to manage well on the outside, even though they are struggling with symptoms internally.

It’s important to note that high-functioning depression is not an official clinical diagnosis. Instead, the term emphasizes the experience of living with depression while still functioning or meeting the demands of everyday life.

The symptoms of high-functioning depression are generally similar to those of major depressive disorder; however, the intensity and frequency may vary, with symptoms sometimes considered mild or moderate. These symptoms can include:

Feelings of hopelessness
Persistent sadness
Irritability
Loss of interest or pleasure
Difficulty concentrating
Trouble sleeping
Fatigue
Changes in appetite

Although the intensity or frequency of symptoms in individuals who seem high-functioning may not be debilitating, they should not be overlooked. It is crucial to seek help. There is no shame in reaching out to a mental health professional and building a support system.

Treatment for depression may include a combination of psychotherapy or talk therapy, medications, brain stimulation therapies, complementary medicine, or lifestyle modifications.

To schedule an appointment with a mental health provider at Jamaica Hospital Medical Center, please call 718-206-5575.

Infant Botulism

Posted on December 1, 2025 by Patrick Hercules

Infant botulism is a rare, life-threatening condition that causes a slow form of paralysis. It affects infants under one year old.

Infant botulism differs from botulism in older children and adults as it develops slowly and worsens gradually. Recognizing symptoms early and seeking medical care promptly can make a significant difference in treatment and recovery. Symptoms of infant botulism can include:

Respiratory difficulty and possible respiratory arrest

Choking when trying to feed

Constipation

Weak or poor feeding

Eyelid drooping

Lack of facial expressions, being unable to lift their head, or other signs of muscle weakness or paralysis

Weak and altered crying

Weakness or decreased muscle tone, which prevents them from reaching or grabbing

Changes in bowel movement, such as not pooping for days or weeks at a time

Since infants cannot express how or what they are feeling, it is essential to recognize and be aware of potential warning signs.

Infants can contract botulism if they eat something, such as honey, that contains spores from the bacteria Clostridium botulinum, which is why infants under a year old should never be given honey. A recent outbreak of infant botulism is suspected to be linked to the contamination of infant formula. When an infant ingests Clostridium botulinum, the bacteria multiply and make a toxin, which disrupts the infant’s nervous system after entering its bloodstream, causing symptoms of botulism.

Infants under a year old are at a higher risk of contracting botulism, with 95% of cases occurring in infants younger than six months old.

A healthcare provider can diagnose infant botulism by observing symptoms and performing physical and neurological exams. Testing stool for botulinum toxin is the best way for a healthcare provider to confirm a diagnosis.

Infant botulism is treatable with an antitoxin called botulism immune globulin, which is administered through an IV.

The Department of Pediatrics at Jamaica Hospital Medical Center provides comprehensive healthcare to infants, children, and adolescents. If your infant is experiencing symptoms of botulism, you can make an appointment by calling 718-206-7001.

How Long Should You Keep Thanksgiving Leftovers?

Posted on November 28, 2025 by Patrick Hercules

It is the day after Thanksgiving, and the refrigerator is full of leftovers. It is important to know how long these leftovers should actually last to avoid foodborne illnesses.

The U.S. Department of Agriculture’s (USDA) Food and Safety and Inspection Service recommends throwing out refrigerated leftovers after three to four days. If certain foods are kept in the freezer, they can still be eaten for three to four months after Thanksgiving.

It is important to properly store and refrigerate all leftovers within two hours at 40 degrees Fahrenheit or colder. To store them, pack the leftovers into small containers and resealable plastic bags. Storing food in smaller portions makes it easier and more convenient for them to be used when taken straight from the freezer. Using freezer or storage-specific plastic bags and plastic wrap helps prevent freezer burn because they are thicker than normal bags. Push out as much air as possible to limit any exposure to the surface of the food, which also helps prevent freezer burn.

Throw away any food that doesn’t keep well in the refrigerator, such as salads, which can become soggy and wilted. Greens such as kale and cabbage can last for up to three days.

Remove any stuffing from inside the turkey and store it separately in airtight containers. Stuffing can last up to four days in the refrigerator and two to three months in the freezer.

When storing leftover turkey, cut the turkey into smaller pieces and store them separately in small airtight containers. Turkey can last for four days in the fridge and four months in the freezer.

Gravy can last for four days in the fridge and up to four months in the freezer. When reheating the gravy, add it to a saucepan and cover it with a lid, and bring it to a rolling boil.

Homemade cranberry sauce can stay good for a week to 10 days in the fridge. Canned cranberry sauce can be kept for up to two weeks when stored in an airtight container and refrigerated. It is not recommended to freeze cranberry sauce.

Potatoes and yams can be stored in the refrigerator for four days and up to two months in the freezer.

Desserts such as fruit pies can be kept at room temperature for two days. After two days, they can be stored in the refrigerator, loosely covered, for two more days.

It is important to note that you should always reheat leftovers to 165 degrees Fahrenheit, as it destroys most foodborne pathogens, preventing you from developing food poisoning.

If you or a loved one is experiencing symptoms of food poisoning, you can receive treatment at Jamaica Hospital Medical Center’s Ambulatory Care Center. Please call (718) 206-7001 to schedule an appointment.

Healthy Holiday Recipe: Rustic Apple Pie with Dried Cherries

Posted on November 26, 2025 by Patrick Hercules

Tomorrow is Thanksgiving, and we all look forward to what’s for dessert after a delicious meal.

Apple pie is a dessert commonly found on a Thanksgiving dessert table. Apples are high in fiber and vitamin C. Adding cherries to an apple pie provides an additional source of antioxidants, making this dessert a heart-healthy choice.

Here is a recipe for a rustic apple pie that combines fresh apples with tangy dried cherries for a unique twist on a Thanksgiving classic.

Rustic Apple Pie with Dried Cherries Recipe | Ellie Krieger | Food Network

Lung Cancer Awareness Month

Posted on November 21, 2025 by Patrick Hercules

November is Lung Cancer Awareness Month, an annual observance dedicated to increasing awareness about lung cancer, its risk factors, early detection, and treatment options.

Lung cancer is the number one cause of cancer death, claiming more lives each year than breast, prostate, ovarian, and kidney cancers combined.

Lung cancer is a kind of cancer that starts with the growth of cells in the lungs. It doesn’t usually cause symptoms early on; however, the symptoms of lung cancer occur when the disease is advanced. Signs and symptoms of lung cancer that happen in and around the lungs include:

A new cough that doesn’t go away

Chest pain

Coughing up blood

Hoarseness

Shortness of breath

Wheezing

In addition to the signs and symptoms of lung cancer in the lungs, some symptoms occur when the cancer spreads to other parts of the body, including:

Bone pain

Headaches

Losing weight without trying

Loss of appetite

Swelling in the face or neck

Lung cancer occurs when cells in the lungs develop changes in their DNA. A cell’s DNA holds instructions that tell a cell what to do. In healthy cells, the DNA gives instructions to grow and multiply at a set rate. The instructions also tell the cells to die at a set time.

In cancer cells, DNA changes give different instructions. The changes tell the cancer cells to make many more cells quickly. Cancer cells can keep living when healthy cells die, causing too many cells.

Cancer cells might form a tumor. The tumor can grow to invade and destroy healthy body tissue. In time, cancer cells can break away and spread to other parts of the body, causing metastatic cancer.

Smoking causes most lung cancer. It can cause lung cancer in both smokers and non-smokers who have been exposed to secondhand smoke. However, people who have never smoked or been exposed to secondhand smoke can develop lung cancer.

Researchers believe smoking causes lung cancer by damaging the cells that line the lungs. Cigarette smoke contains cancer-causing substances known as carcinogens. When cigarette smoke is inhaled, carcinogens immediately cause changes in the lung tissue. The body may be able to repair the damage at first, but with each repeated exposure, healthy cells lining the lungs become more damaged. Over time, the damage causes cells to change, eventually developing into cancer.

Lung cancer is divided into two major types based on the appearance of cells under a microscope. The two general types of lung cancer include:

Small-cell lung cancer

Non-small cell lung cancer

A lung cancer diagnosis often starts with an imaging test to look at the lungs for signs of cancer before it develops. Other tests used to diagnose lung cancer include:

Sputum cytology

Biopsy

There are also additional tests that can be performed if a person is diagnosed with lung cancer to see if the cancer has spread. These tests allow a healthcare provider to know what stage the cancer is in. The stages of lung cancer range from 1 to 4. These staging tests often involve imaging tests such as an MRI, CT scan, bone scans, and a PET scan. If the cancer is in stage 1, the cancer is small and only in the lung. As cancer grows larger or spreads outside of the lungs, the numbers get higher. Stage 4 lung cancer means the cancer has spread to other parts of the body.

Treatment for lung cancer usually begins with surgery to remove the cancer. However, if the cancer is very large or has spread to other parts of the body, surgery may not be possible. As an alternative, treatment may start with medicine and radiation instead. A healthcare team will consider many factors when creating a treatment plan. These factors may include:

Overall health

The type and stage of cancer

The patient’s preferences

Another type of treatment for lung cancer is palliative care. Palliative care specialists will work with the patient, their family, and healthcare team to provide extra support while the patient goes through their cancer treatment.

Unfortunately, there isn’t a sure way to prevent lung cancer. However, you can reduce your risk by not smoking or quitting smoking, avoiding secondhand smoke, eating a diet of fruits and vegetables, and exercising most days of the week.

If you would like to learn more about lung cancer treatments, or to learn more about our cancer care program, you can schedule an appointment with an oncologist at our MediSys Health Network Cancer Center by calling (718) 206-6742.

Meet Our Doctors- Dr. Andrew Bi

Posted on November 17, 2025 by Patrick Hercules

Jamaica Hospital Medical Center is proud to introduce Dr. Andrew Bi, the newest member of our orthopedic surgical team.

Dr. Bi was born in Chicago, Illinois, and raised in East Lyme, Connecticut, and currently resides in Queens. He graduated from the University of Connecticut magna cum laude with honors. He then graduated from Northwestern University Feinberg School of Medicine summa cum laude with Alpha Omega Alpha honors. Then he completed his orthopedic surgery residency training at NYU Langone Orthopedics, where he served as Executive Chief Resident. Dr. Bi later underwent subspeciality training at Midwest Orthopaedics at Rush in a sports medicine fellowship, where he served as assistant team physician for the Chicago Bulls, Chicago White Sox, Chicago Steel, and DePaul University.

Dr. Bi has received numerous awards for teaching, clinical care, and research, including the Ralph Lusskin Senior Resident Teaching Award, the Marian Frauenthal Sloane Clinical Research Award, and the Rush Annual Thesis Day Award.

Dr. Bi treats all aspects of orthopedic injuries with a special interest in the management of all shoulder, elbow, hip, and knee conditions, including, but not limited to robotic-assisted joint replacements for arthritis, minimally invasive arthroscopic surgeries for sports injuries, such as anterior cruciate ligament (ACL), meniscus, cartilage, rotator cuff, and labrum injuries, and the fixation of fractures. His current research efforts involve anterior cruciate ligament injuries, meniscal allograft transplantations, rotator cuff tears, hip arthroscopy, and orthobiologics.

Dr. Bi is excited to begin at the Medisys family at Jamaica Hospital, bringing with him expertise in sports medicine subspecialization, as well as his Chinese heritage, to care for the diverse population surrounding the hospital.

If you are experiencing any illnesses or injuries affecting your bones, muscles, ligaments, and tendons, you can schedule an appointment at Orthopedic Specialists of New York by calling 718-206-6923

Foods Rich In Magnesium

Posted on November 14, 2025 by Patrick Hercules

Magnesium is a mineral that can be found in various foods. It helps support more than 300 different chemical processes throughout the human body, such as:

Muscle function

Regulating blood pressure and blood sugar levels

Promoting energy production

Nerve function and bone health

Mental health

When eating foods containing magnesium, experts recommend consuming between 310 and 420 milligrams (mg) of magnesium per day, depending on age and sex:

Babies 6 months and younger: 30 mg

7 to 12 months: 75 mg

1 to 3 years old: 80 mg

4 to 8 years: 130 mg

9 to 13 years 240 mg

14 to 18 years (male): 410 mg

14 to 18 years (female): 360 mg

19 to 30 years (male): 400 mg

19 to 30 years (female): 310 mg

31 and older male: 420 mg

31 and older female: 320 mg

Pregnant women should get an additional 40 mg of magnesium per day. Some, but not all, prenatal vitamins include magnesium.

Many foods contain magnesium, including:

Nuts and seeds:

- Roasted almonds- 1oz = 80 mg of magnesium

- Roasted cashews- 1oz = 72 mg of magnesium

- Whole flaxseeds- 1 Tbsp = 40 mg of magnesium

- Dry roasted peanuts- 1 oz = 49 mg of magnesium

- Hulled and roasted pumpkin seeds- 1 oz = 15 mg of magnesium

- Chia seeds- 1oz = 111 mg magnesium

Legumes:

- Boiled black beans- ½ cup = 60 mg of magnesium

- Cooked and prepared edamame- ½ cup = 50 mg of magnesium

- Cooked lima beans- ½ cup = 40 mg of magnesium

Fiber-rich whole grains:

- Cooked quinoa- ½ cup = 60 mg of magnesium

- Plain, unfrosted shredded wheat- 1 cup = 56 mg of magnesium

Low-fat dairy products:

- Nonfat milk- 1 cup = 24 to 27 mg of magnesium

- Plain low-fat yogurt- 8oz = 42 mg of magnesium

Greens:

- Cooked spinach- ½ cup = 78 mg of magnesium

- Cooked Swiss chard- ½ cup = 75 mg of magnesium

- Collard greens- ½ cup = 25 mg of magnesium

Fruit:

- One whole avocado = 58 mg of magnesium

- One medium banana = 32 mg of magnesium

- One small papaya = 33 mg of magnesium

- Blackberries- 1 cup = 29 mg of magnesium

Vegetables:

- Green peas- ½ cup = 31 mg of magnesium

- Sweet corn- ½ cup = 27 mg of magnesium

- One medium potato with skin on = 48 mg of magnesium

Dark chocolate that is 70%-85% cocoa- 1oz = 64 mg of magnesium

2 liters of water- up to 240 mg of magnesium

If you have a magnesium deficiency, a healthcare provider may suggest magnesium supplements. When magnesium is combined with other substances, it can help bring out specific benefits, including:

Magnesium glycinate: helps promote sleep

Magnesium citrate: helps digestion

Magnesium oxide: an antacid and aid to relieve migraines

Magnesium sulfate (Epsom salt): used as a muscle relaxant

Eating a meal that contains magnesium-rich foods is the foundation of a healthy diet and is beneficial for your overall health.

It is important to note that you should first speak with your doctor about making any changes to your diet and before taking any new supplements. To consult a physician about the best ways to get your daily amount of magnesium, you can schedule an appointment at Jamaica Hospital Medical Center’s Ambulatory Care Center. Please call (718) 206-7001.

Warning Signs of Blood Clots

Posted on November 12, 2025 by Patrick Hercules

Blood clots are gel-like clumps of blood that have partially solidified in a blood vessel. Clotting is a natural and essential process that stops bleeding when you’re injured. However, some blood clots can form anywhere along the 60,000 miles of blood vessels in the body and are most likely to happen in the veins. These are called venous blood clots. The most common kinds of venous blood clots are:

Deep vein thrombosis (DVT)- DVT usually forms in the legs in the deep veins of the body. Thrombosis is when clots stay put and block blood flow.

Pulmonary embolism (PE)- Embolisms are blood clots that break free and travel to other parts of the body. If a DVT breaks off and travels to the lungs, it can create a pulmonary embolism.

Arterial clots are less common, occurring when a blood clot clogs an artery. These clots can block oxygen from reaching the heart or brain, which can lead to a heart attack or stroke.

Anyone can develop a blood clot; however, certain factors can increase the risk of developing them, including:

Prolonged immobility, such as during long flights or hospital stays

Surgery, especially involving the legs, hips, or abdomen

Pregnancy and the postpartum period

Hormonal birth control or hormone replacement therapy

Smoking

Obesity

Family history of blood clots or clotting disorders

Cancer or cancer treatments

Recognizing the signs and symptoms of a blood clot can be lifesaving. Here are the signs and symptoms to watch out for:

Swelling in one limb

Pain or tenderness in the affected area

Red or discolored skin

Warmth in the skin

Sudden shortness of breath

Chest pain

Coughing, possibly with blood

Rapid heartbeat or palpitations

Leg fatigue or heaviness

Dizziness or fainting

Blood clots are known to be silent killers as their symptoms can be similar to symptoms of other, less serious conditions. That’s why it is crucial to understand and recognize the signs and symptoms of blood clots, especially if you are at an increased risk of developing them. Awareness and timely action can help prevent major complications from a stroke, pulmonary embolism, or heart attack.

If you are experiencing symptoms of a blood clot or think you may be at risk of developing one, you can schedule an appointment with one of our vascular surgeons in NYC or learn more about the services at our vascular surgery center in New York. Please call 718-206-6713.

Best Sleep Postures

Posted on November 7, 2025 by Patrick Hercules

Everyone has a particular position they use while sleeping. However, people frequently overlook the importance of their sleeping position.

Your sleep posture can influence how your body feels, the quality of your sleep, and even certain health conditions. Finding the right sleep position can relieve stress on the spine and joints, and may also impact factors such as a person’s breathing and risk of heartburn.

The best sleep position is one that promotes healthy spine alignment from the hips to the head. What works best for a person depends on their health situation and what they find comfortable.

Some sleep positions are healthier than others. For example, sleeping on the side or back is considered more beneficial than sleeping on the stomach. In either of these positions, it is easier to keep your spine supported and balanced because it relieves pressure, allowing the muscles to relax and recover.

Spinal support is only one part of the equation. Sleeping positions can also have effects on a range of health issues, including sleep apnea, acid reflux, and pain.

If a person is suffering from sleep apnea, the best sleep position to help reduce symptoms is to sleep on their side or stomach because it keeps their airways open while they sleep.

For a person with heartburn and gastroesophageal reflux disease (GERD), the best sleeping position is on their left side, which helps make it harder for stomach acid to reach the junction between the stomach and esophagus.

Sleeping on your side with your knees slightly bent with a small pillow between them is the best sleeping position for someone who has lower back pain, which allows the entire spine to stay in a neutral position, and that spinal alignment helps reduce neck and back pain.

To help someone relieve their neck pain, the best sleeping position is on their back with their arms in a similar position. This reduces the overactivity of the muscles around the neck and doesn’t put more pressure on one side of their body.

If someone is experiencing both hip and knee pain, they can reduce the pain by sleeping on their side with a pillow between their knees, which can keep the hips, pelvis, and spine aligned, easing pressure on joints and muscles.

For women who are pregnant, the best sleeping position is on their left side with their knees bent, which improves circulation, making it easier for nutrient-rich blood to reach the placenta, and can help reduce pressure on the liver and lower back. It may also help ease swelling in the legs, feet, and hands.

When a person has allergies or a stuffy nose, sleeping upright is the best sleeping position to help their airways stay open, allowing the stuffy nose to drain.

Getting a good night’s sleep is important to your health and well-being. However, sometimes the position you choose to sleep in can cause or worsen breathing problems, such as sleep apnea, or aggravate back and neck pain. If any of these conditions arise, you may want to try to sleep in a different position.

If you are having difficulty sleeping and would like help, Jamaica Hospital’s state-of-the-art sleep center can help diagnose and treat various sleep disorders. For more information or to make an appointment, please call 718-206-5916.