How to Improve Your Gut Health and Balance Your Gut Microbiome

Posted on June 19, 2026 by Patrick Hercules

There are trillions of beneficial bacteria living in your gut, or gut microbiome, that are essential to your health and well-being. The gut microbiome plays an important role in strengthening your immune system and regulating daily bodily functions, including hunger signals and mood fluctuations.

The gut contains 95 percent of the feel-good hormone, serotonin, which means what you eat can impact your ability to respond to stress, reduce anxiety, and help the body fight off germs, viruses, and bacteria that could make you sick.

When you have an unhealthy gut, it can cause several diseases and conditions, including:

Inflammatory bowel disease

Obesity

Small intestinal bacterial overgrowth

Insulin resistance and other endocrine disorders

Mental health conditions and neurological disorders

Asthma

Various cancers

There can be several signs of an unhealthy and imbalanced gut, including:

Intolerance to certain foods

A frequent upset stomach

Intense cravings

Skin irritations

Autoimmune disorders

Intense cravings

Migraines and frequent headaches

Difficulty sleeping or excessive fatigue

Irritability or other mood changes

Changes in bathroom habits

The most direct and effective way to improve your gut health is through your diet by getting enough dietary fiber. Dietary fiber is the key nutrient for maintaining the diversity of gut microbiota. Having low gut microbiota diversity is associated with many chronic inflammatory diseases, such as:

Obesity

Diabetes

Irritable bowel disease (IBD)

Several foods are high in fiber, including:

Fruits

Vegetables

Nuts

Whole grains, such as:

Barley

Bran

Quinoa

Oatmeal

Brown rice

Seeds

Legumes, including peas, beans, and lentils

Other recommendations for improved gut health include:

Increasing consumption of whole foods by adopting the Mediterranean diet

Limiting processed foods

Eating smaller meals

Eating more slowly and chewing food thoroughly

Managing stress

Exercising more

Setting a gut bedtime

Gut health can also be improved by taking probiotics and prebiotics.

Probiotics are “good” bacteria and other microorganisms that reside in the gut and are believed to support a healthy immune system and good digestion. Probiotics can be found in fermented foods, including:

Yogurt

Kefir

Sauerkraut

Kombucha

Pickles that are salt-based

Tempeh

Kimchi

Miso

Prebiotics are dietary fibers that probiotics feed on. They can be found in several high-fiber foods, including:

Leeks

Asparagus

Garlic

Onions

Bananas

Chicory root

The Academy of Nutrition and Dietetics recommends that women aim for 25 grams of fiber per day and men for 38 grams per day.

If you would like to improve your gut health and balance your gut microbiome, you can consult a physician by visiting Flushing Hospital Medical Center’s Ambulatory Care Center. To schedule an appointment, please call (718) 670-5486.

All content of this newsletter is intended for general information purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Please consult a medical professional before adopting any of the suggestions on this page. You must never disregard professional medical advice or delay seeking medical treatment based upon any content of this newsletter. PROMPTLY CONSULT YOUR PHYSICIAN OR CALL 911 IF YOU BELIEVE YOU HAVE A MEDICAL EMERGENCY.

The Dangers of Misusing the Allergy Medication Diphenhydramine

Posted on June 12, 2026 by Patrick Hercules

When people are experiencing allergy symptoms such as coughs, sneezes, a runny nose, congestion, and itchy eyes, nose, or throat, they turn to allergy medications like diphenhydramine to help quell them. Diphenhydramine is an over-the-counter (OTC) antihistamine that, when used as directed, is usually safe for occasional allergy or sleep symptoms. However, when diphenhydramine is misused and more than the recommended dosage is taken, it can cause serious health risks.

According to the Centers for Disease Control and Prevention (CDC), an estimated one million people are seen in U.S. hospital emergency departments for adverse drug events each year, and more than one-fourth are hospitalized.

Unfortunately, teenagers have been reportedly taking dangerously high doses of diphenhydramine intentionally to provoke hallucinations. In 2020, the U.S. Food and Drug Administration (FDA) warned that taking higher doses of diphenhydramine could lead to life-threatening complications, including heart problems, such as irregular heart rhythms, seizures, coma, or even death, after news reports of teenagers being admitted to emergency rooms or dying after a TikTok challenge encouraged them to misuse the allergy medication.

In addition to life-threatening complications, misusing diphenhydramine can lead to cognitive decline, psychiatric harm, and neurological injury.

The FDA recommends always reading the drug facts label on all over-the-counter medicines to find out if they contain diphenhydramine, how much and how often you should take them, and important safety information to avoid taking more than the dose listed and prevent serious health risks.

Here are some safety tips to reduce the risk of the potentially harmful effects of misusing diphenhydramine:

Lock medicine away safely to prevent accidental poisoning

Choose medicines that only treat the symptoms you have

Be mindful that many medicines contain multiple ingredients that may interact with alcohol dangerously

Look out for the same active ingredients in medicines taken at the same time, as it may result in an overdose

Do not take medicines longer than needed or in higher doses

Do not take medicines with side effects that impact your ability to drive safely or use heavy machinery until you are in an appropriate and safe environment

Read the dosing directions carefully, especially when it comes to infants and children

Be cautious when taking more than one medicine at a time, as drug-to-drug interactions can cause serious health effects and can even be fatal

If you or a loved one is experiencing a bad reaction or serious side effects to an allergy medication, you can schedule an appointment with a doctor at Jamaica Hospital Medical Center’s Ambulatory Care Center. Please call (718) 206-7001. Please call 911 if there is an emergency.

Aphasia Awareness Month

Posted on June 11, 2026 by Patrick Hercules

June is National Aphasia Awareness Month, a month dedicated to increasing understanding of aphasia. This acquired communication disorder impairs a person’s ability to process language but does not affect their intelligence.

Aphasia affects the ability to speak and understand others, causing most people with the disorder to have trouble reading and writing.

The most common cause of aphasia is stroke. About 25 to 40 percent of stroke survivors are afflicted with aphasia. It can also be a result of a head injury, a brain tumor, or other neurological causes.

There are six types of aphasia, including:

Global aphasia is the most severe form of aphasia and is applied to patients who can produce few recognizable words and understand little or no spoken language. People with global aphasia can’t read or write. It is often seen immediately after the patient has suffered a stroke and may rapidly improve if the damage to the brain has not been too extensive. However, with greater brain damage, there may be severe and lasting disability.

Broca’s aphasia, or non-fluent aphasia, is a form of aphasia in which the speech output is severely reduced and is limited mainly to short utterances of less than four words. A person’s vocabulary access is limited, and so is their ability to form sounds.

Mixed non-fluent aphasia is a form of aphasia that applies to people with sparse and effortful speech, which can resemble severe Broca’s aphasia. However, they remain limited in their speech comprehension and do not read or write beyond an elementary level.

Wernicke’s aphasia, or fluent aphasia, is a form of aphasia in which the ability to grasp the meaning of spoken words is impaired. However, the ease of producing connected speech is not much affected. Reading and writing are often severely impaired.

Anomic aphasia is a form of aphasia that is applied to people left with a persistent inability to supply the words for the things they want to say, particularly significant nouns and verbs.

Primary progressive aphasia (PPA) is a neurological syndrome in which language capabilities become slowly and progressively impaired. Unlike the other forms of aphasia that result from stroke or brain injury, PPA is caused by Alzheimer’s or frontotemporal lobar degeneration.

A healthcare provider can diagnose aphasia by performing physical and neurological exams. They can also use imaging tests, such as an MRI and a CT scan, to identify what is causing aphasia.

Aphasia can also be diagnosed with the help of a speech-language pathologist who can complete a comprehensive language assessment to confirm the presence of aphasia and determine the appropriate course of language treatment.

The assessment helps find out whether the person can:

Name common objects

Engage in a conversation

Understand and use words correctly

Answer questions about something read or heard

Repeat words and sentences

Follow instructions

Answer yes and no questions and respond to open-ended questions about common subjects

Read and write

There are several treatments for aphasia, including:

Speech and language rehabilitation therapy aims to improve the ability to communicate and help restore as much language as possible. This is done by teaching the person with aphasia how to make up for lost language skills and find other communication methods. This therapy:

Starts early

Often works in groups

May include the use of computers

Medications are being studied to treat aphasia that may improve blood flow to the brain and enhance its ability to recover or help replace the depleted chemicals in the brain.

Brain stimulations, such as transcranial magnetic and direct current stimulation, are being studied to help improve the ability to name things.

Because aphasia is often a sign of a serious problem, such as a stroke, seek emergency medical care if you suddenly develop any symptoms.

If you are experiencing any symptoms of aphasia, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.

Men’s Health Month- Health Screenings for Men

Posted on June 10, 2026 by Patrick Hercules

June is Men’s Health Month. This observance aims to raise awareness about preventable health problems that affect men and boys.

Statistics show men are less likely than women to seek medical attention when something affects their health. Men are also less likely to have preventative screenings and checkups with their healthcare providers. This is a problem as early detection of a medical condition is the best way to effectively treat and manage it.

Additionally, avoiding or delaying checkups or screenings could result in a treatable condition becoming severe and/or fatal.

The U.S. Preventative Services Task Force (USPSTF) publishes a list of recommended, age-specific screening guidelines for men to help them manage their health:

Screenings guidelines recommended for men ages 18-39 include:

Physical examinations

Blood pressure screenings

Cholesterol screenings

Colon cancer screenings

Dental examinations

Prediabetes and type 2 diabetes screenings

Eye examinations

Immunizations

Skin examinations

Infectious disease screenings

Screenings guidelines recommended for men ages 40-64 include:

Physical examinations

Blood pressure screenings

Cholesterol screenings

Colorectal cancer screenings

Prostate cancer screenings

Osteoporosis screening

Lung cancer screening

Infectious disease screening

Immunizations

Eye examinations

Dental examinations

Skin examinations

It is important to visit your healthcare providers regularly, even if you are feeling healthy. These visits can help:

Screen for any medical issues

Encourage a healthy lifestyle

Assess your risk for any future medical problems

Update vaccinations and other preventative care services

Help you get to know your healthcare provider in case of an illness

If you are experiencing any medical problems or would like to receive health screenings, you can schedule an appointment at Jamaica Hospital Medical Center’s Ambulatory Care Center, by calling (718) 206-7001.

Restless Leg Syndrome

Posted on May 7, 2026 by Patrick Hercules

Restless legs syndrome (RLS), or Willis-Ekbom disease, is a condition that causes a strong urge to move the legs, typically accompanied by an uncomfortable sensation. This sensation usually occurs in the evening or at night when sitting or lying down. Moving the legs eases the discomfort for a short time.

There are two types of restless leg syndrome: early onset and late onset.

Early onset restless leg syndrome is diagnosed before the age of 45, usually runs in your biological family, and progresses slowly.

Late-onset restless leg syndrome is diagnosed after the age of 45 and progresses more quickly.

Restless leg syndrome affects between 7% and 10% of the U.S. population and is more common among Caucasian people and females.

The symptoms of restless leg syndrome include:

An uncomfortable sensation in the legs that causes the urge to move them

A temporary feeling of relief when the legs move

Sensations that worsen while resting

Twitchy legs or leg jerks in the evening and while sleeping

Restless leg syndrome symptoms can affect sleep and can cause:

Sleep disruptions, difficulty falling or staying asleep

Fatigue or daytime sleepiness

Behavior or mood changes

An urge to get out of bed to stretch or move the legs

Depression or anxiety

Difficulty paying attention, remembering things, or concentrating

When a person experiences restless leg syndrome, they feel sensations that make them want to move their legs and feet. These sensations include:

Crawling

Itching

Aching

Throbbing

Pulling or tugging

Burning

There isn’t a known cause for restless leg syndrome. However, researchers believe it may be caused by an imbalance of dopamine, the brain chemical that sends messages to control muscle movement.

Other factors that may contribute to the risk of developing restless leg syndrome include:

Genetics

Medications, such as antihistamines, antidepressants, or anti-nausea medications

Having an underlying medical condition, such as an iron deficiency

Other medical conditions can cause restless leg syndrome, including:

Anemia

Pregnancy

Diabetes

Kidney disease

Peripheral neuropathy

Substance abuse disorder

There are several triggers, such as alcohol, caffeine, nicotine, stress, and certain medications, that can make restless leg syndrome symptoms worse.

To diagnose restless leg syndrome, a healthcare provider will perform a physical exam to review your symptoms and ask about your medical and family medical history. They may also perform a neurological exam, blood tests, and recommend an overnight sleep study. The criteria they will use to confirm a diagnosis of restless leg syndrome include:

You have the urge to move your legs, usually occurring with uncomfortable sensations like aching or pulling.

Symptoms begin or worsen during periods of rest or inactivity.

You have partial or total relief when stretching, walking, or exercising the affected muscles.

Your symptoms are worse or only occur in the evening or at night.

Another medical condition didn’t cause your symptoms.

Treating restless leg syndrome includes taking medications or changing your routine at home by following recommended at-home therapies to help relieve your symptoms and help you feel more comfortable.

If you are experiencing any symptoms of restless leg syndrome, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.

Lupus Awareness Month

Posted on May 6, 2026 by Patrick Hercules

May is observed as Lupus Awareness Month, a month used to educate, advocate, and support those affected by lupus.

Lupus is an autoimmune disease that occurs when the body’s immune system attacks its tissues and organs. Inflammation caused by lupus can affect many different body systems, such as the joints, skin, kidneys, blood cells, brain, heart, and lungs.

Healthcare providers sometimes call lupus systemic lupus erythematosus (SLE). It is the most common type of lupus, which means you have lupus throughout your body. Other types of lupus include:

Cutaneous lupus erythematosus- is lupus that only affects your skin

Drug-induced lupus- occurs when some medications trigger lupus symptoms as a side effect. It is usually temporary and might go away after you stop taking the medication that caused it

Neonatal lupus- occurs when babies are sometimes born with lupus. Babies born to biological parents with lupus aren’t certain to have lupus, but they might have an increased risk

No two cases of lupus are exactly alike. Signs and symptoms may come suddenly or develop slowly, may be mild or severe, and may be temporary or permanent. Most people with lupus have a mild form of the disease characterized by flare-ups, when signs and symptoms may get worse for a while, and then improve or disappear completely for a time.

The signs and symptoms of lupus you experience will depend on which body systems are affected by the disease. The most common signs and symptoms include:

Fatigue

Fever

Joint pain, stiffness, and swelling

A butterfly-shaped rash on the face that covers the cheeks and bridge of the nose, or rashes elsewhere on the body

Skin lesions that appear or worsen with sun exposure

Fingers and toes that turn white or blue when exposed to cold or during stressful periods

Shortness of breath

Chest pain

Dry eyes

Headaches, confusion, and memory loss

Lupus likely results from a combination of genetics and the environment.

People with an inherited predisposition for lupus may develop the disease when they come into contact with an environmental trigger of the disease. Some potential triggers of lupus include:

Sunlight

Infections

Diagnosing lupus is difficult because signs and symptoms can vary from person to person and may change over time, overlapping with those of many other disorders.

No one test can diagnose lupus. The combination of blood and urine tests, signs and symptoms, and results of a physical examination can lead to a diagnosis. Blood and urine tests may include:

A complete blood count

Erythrocyte sedimentation rate

Kidney and liver assessment

Urinalysis

Antinuclear antibody (ANA) test

If your healthcare provider suspects that lupus is affecting your lungs or heart, they may suggest imaging tests that can include:

A chest X-ray

An echocardiogram

Lupus can harm the kidneys in many ways, and treatments can vary depending on the type of damage it causes. Sometimes, a kidney biopsy is needed to determine the best treatment. A skin biopsy can be performed to confirm a diagnosis of lupus affecting the skin.

A healthcare provider will suggest treatments for lupus that manage your symptoms. The goal is to minimize damage to the organs and how much lupus affects your day-to-day life. Most people with lupus need a combination of medications to help them prevent flare-ups and lessen the severity of symptoms during a flare-up. Medications you might need include:

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Corticosteroids

Antimalarial drugs

Immunosuppressants

Biologics

Simple measures can help prevent lupus flare-ups if they occur, and help you to better cope with the signs and symptoms you experience, including:

Seeing your doctor regularly

Being sun smart

Getting regular exercise

Quitting smoking

Eating a healthy diet

Asking your healthcare provider if you need vitamin D and calcium supplements

If you would like to participate in Lupus Awareness Month, here are some ways you can do so:

Learn about lupus

Support those who are suffering from lupus

Advocate for better research, more care, and more compassion

For more information about the Lupus Center at the campus of Jamaica Hospital Medical Center or to make an appointment with a lupus doctor, call (718) 206-9888.

REM Sleep Behavior Disorder

Posted on April 10, 2026 by Patrick Hercules

Rapid eye movement (REM) sleep behavior disorder occurs when a person unknowingly, physically acts out their vivid, often bad dreams with vocal sounds and sudden, often violent arm and leg movements during REM sleep.

People don’t normally move during REM sleep, which is a normal stage of sleep that occurs many times during the night.

About 20% of a person’s sleep is REM sleep, the usual time when dreaming occurs, primarily during the second half of the night.

REM sleep behavior disorder may be linked to neurological conditions, such as:

Lewy body dementia
Parkinson’s disease
Multiple system atrophy

The onset of REM sleep behavior disorder can be gradual or sudden, and it can worsen over time. Episodes of the disorder occur occasionally or several times a night.

Symptoms of REM sleep behavior disorder include:

Movements, such as kicking, punching, arm flailing, or jumping from bed, in response to action-filled or violent dreams, such as being chased or fighting off an attack
Noises, such as talking, laughing, shouting, emotional outcries, or even cursing
Being able to recall the dream if awoken during the episode

Usually, the nerve pathways in the brain that prevent muscles from moving are active during normal REM sleep, which results in temporary paralysis of the body. However, in REM sleep behavior disorder, the nerve pathways no longer work, causing a person to physically act out their dreams.

There are several risk factors associated with the development of REM sleep behavior disorder, including:

Having a certain type of neurodegenerative disorder
Taking certain medications
Having narcolepsy
Being male and over 50 years old

Additionally, recent evidence indicates there may also be several specific environmental or personal risk factors for REM sleep behavior disorder, including:

Occupational pesticide exposure
Farming
Smoking
A previous head injury

REM sleep behavior disorder can cause various complications, including:

Injury to yourself or your sleeping partner
Distress to your sleeping partner or other people living in your home
Social isolation for fear that others may become aware of your sleep disruption

To diagnose REM sleep behavior disorder, a healthcare provider reviews your medical history and symptoms. The evaluation can include:

Physical and neurological exam
Nocturnal sleep study
Talking with your sleeping partner

A healthcare provider uses the symptom criteria in the International Classification of Sleep Disorders, Third Edition (ICSD-3). The criteria include:

You have repeated times of arousal during sleep where you talk, make noises, or perform complex motor behaviors, such as punching, kicking, or running movements, that often relate to the content of your dreams
You recall dreams associated with these movements or sounds
If you awaken during an episode, you are alert and not confused or disoriented
A sleep study shows you have an increase in muscle activity during REM sleep
Your sleep disturbance is not caused by another disturbance, a mental health disorder, medication, or substance abuse

REM sleep behavior disorder can be the first indication of the development of a neurodegenerative disease, such as Parkinson’s disease, multiple system atrophy, or dementia with Lewy bodies.

Treatment for REM sleep behavior disorder may include physical safeguards and medications.

Physical safeguards make it safer for you and your bed partner.

Medications such as melatonin and clonazepam can be prescribed to help treat REM sleep behavior disorder.

If you are experiencing any symptoms of REM sleep behavior disorder, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.

World Epilepsy Awareness Day (Purple Day)

Posted on March 26, 2026 by Patrick Hercules

World Epilepsy Awareness Day, or Purple Day, is observed on March 26th, a global initiative to raise awareness of epilepsy and support the millions of people living with it worldwide.

Approximately 65 million people are living with epilepsy across the world, and one in 26 people in the U.S. will be diagnosed with epilepsy during their lifetime.

Epilepsy is a brain condition that causes recurring seizures. Most people who suffer from epilepsy generally have the same type of seizure each time, and symptoms are usually similar from episode to episode. The symptoms of seizures can vary depending on the type of seizure, and because epilepsy is caused by certain activity in the brain, seizures can affect any brain process. Seizure symptoms may include:

Short-term confusion.

A staring spell.

Stiff muscles.

Jerking movements of the arms and legs.

Loss of consciousness.

Psychological symptoms such as fear, anxiety, or déjà vu.

Sometimes people with epilepsy may have changes in their behavior and may also experience psychosis.

Seizures can be categorized as either focal or generalized, based on where in the brain the brain activity that causes the seizure originates.

Focal seizures are the result of brain activity in just one area of the brain. Focal seizures can fall into two categories: focal seizures with preserved consciousness or focal seizures with impaired consciousness.

Types of focal seizures include:

Temporal lobe seizures

Frontal lobe seizures

Occipital lobe seizures

Focal seizures may have warning signs called auras in the moments before a seizure begins. Auras might include a feeling in the stomach, emotions such as fear, or the feeling of déjà vu. They can also be a taste, a smell, or a visual, such as a steady or flashing light, a color, or a shape. Some people may even experience dizziness and loss of balance, or hallucinations.

Generalized seizures are seizures that involve all areas of the brain. Types of generalized seizures include:

Absence seizures

Tonic seizures

Atonic seizures

Clonic seizures

Myoclonic seizures

Tonic-clonic seizures

There is no identifiable cause of epilepsy in about half of the people with the condition. In the other half, the condition may be traced to various factors, including:

Family history of epilepsy

Head trauma

Brain tumors

Infections, such as meningitis, HIV, viral encephalitis, and some parasitic infections

Abnormal blood vessel formation or bleeding in the brain

Alzheimer’s disease

Strokes, heart attacks, and other conditions that deprive the brain of oxygen

Brain inflammation or swelling

Alcoholism or alcohol withdrawal

Injury before birth

Developmental conditions

Seizures can be caused by environmental triggers. These seizure triggers don’t cause epilepsy, but they may trigger seizures in people who suffer from epilepsy. Most people with epilepsy don’t have reliable triggers that always cause seizures. However, there are often factors that make it easier to have a seizure, including:

Flashing lights

Alcohol

Illicit drug use

Lack of sleep

Stress

Dehydration

Skipping doses of anti-seizure medicines or taking more than prescribed

Skipped meals

Illness

Epilepsy is diagnosed when a healthcare provider reviews your symptoms and medical history. They may perform several tests to diagnose epilepsy and to detect the cause of seizures. These tests include:

A neurological exam

Blood tests

Genetic testing

A healthcare provider may also request brain-imaging tests and scans that detect brain changes, including:

Electroencephalogram (EEG)

High-density EEG

CT scan

Functional MRI (fMRI)

PET scan

Single-photon emission computerized tomography (SPECT)

Neuropsychological tests

Along with the test results of these brain-imaging tests, a combination of other techniques may be used to help pinpoint where the seizures start in the brain. They include:

Statistical parametric mapping (SPM)

Electrical source imaging (ESI)

Magnetoencephalography (MEG)

Treatment can help people who have been diagnosed with epilepsy have fewer seizures or even completely stop having seizures. These treatments include:

Medicines

Therapies that include devices that stimulate the brain

Surgery

A ketogenic diet

If you are experiencing any symptoms of epilepsy, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.

Treatments to Reduce Alzheimer’s Disease

Posted on March 18, 2026 by Patrick Hercules

Alzheimer’s disease is a degenerative brain disease and the most common type of dementia. It causes a slow decline in memory, thinking, and reasoning skills. Age is the biggest risk factor for the disease, followed by sex and family history.

There is currently no cure for Alzheimer’s disease. However, there is progress in Alzheimer’s and dementia research that is creating promising new treatments for those living with the disease.

The U.S. Food and Drug Administration (FDA) has approved medications for Alzheimer’s disease, which fall into two categories:

· Drugs that change disease progression in people living with early Alzheimer’s

· Drugs that temporarily ease some symptoms of Alzheimer’s

Drugs that change disease progression target the underlying biology of the disease process by aiming to slow the decline of memory and thinking, as well as function.

Anti-amyloid treatments work by removing a protein that accumulates into plaques in the brain, called beta-amyloid. Each treatment works differently and targets beta-amyloid at a different stage of plaque formation.

These treatments change the course of the disease significantly for those who are in the early stages by giving them more time to be able to participate in daily activities and live independently.

The two treatment therapies that change disease progression are Donanemab and Lecanemab.

Donanemab is an anti-amyloid antibody intravenous (IV) infusion therapy that is delivered every four weeks to treat early Alzheimer’s disease, which includes people who are living with mild cognitive impairment (MCI) or mild dementia due to Alzheimer’s who have been diagnosed with elevated beta-amyloid in the brain.

Donanemab was the third therapy that demonstrated that removing beta-amyloid from the brain decreases cognitive and functional decline in people living with early Alzheimer’s disease.

Lecanemab was the second therapy to demonstrate that removing beta-amyloid from the brain decreases cognitive and functional decline in people living with early Alzheimer’s disease.

It is important to note that anti-amyloid treatments do have side effects, such as allergic reactions, amyloid-related abnormalities (ARIA), infusion-related reactions, headaches, and falls.

As Alzheimer’s progresses, brain cells die, and the connections among those cells are lost. When this occurs, it causes cognitive and noncognitive symptoms to worsen.

Although these medications don’t stop the damage that Alzheimer’s disease causes to brain cells, they may lessen or stabilize symptoms for a limited time by affecting specific chemicals involved in delivering messages among and between the brain’s nerve cells.

The medications that are prescribed to treat symptoms related to memory and thinking include:

Cholinesterase inhibitors are prescribed to treat symptoms related to memory, thinking, language, judgment, and other thought processes. These medications prevent the breakdown of a chemical messenger important for memory and learning, called acetylcholine. Cholinesterase inhibitors support communication between nerve cells. The most prescribed cholinesterase inhibitors include:

· Benzgalantamine treats mild-to-moderate dementia due to Alzheimer’s disease

· Donepezil treats mild-to-severe dementia due to Alzheimer’s disease

· Galantamine treats mild-to-moderate dementia due to Alzheimer’s disease

· Rivastigmine treats mild-to-moderate dementia due to Alzheimer’s disease as well as mild-to-moderate dementia due to Parkinson’s disease

Possible side effects for these medications include:

· Headache

· Dizziness

· Diarrhea

· Increased frequency of bowel movements

· Nausea

· Vomiting

· Loss of appetite

Glutamate regulators are medications prescribed to improve memory, attention, reasoning, language, and the ability to perform simple tasks. This medication regulates the activity of glutamate, a different chemical messenger that helps the brain process information.

Memantine is a glutamate regulator that treats moderate-to-severe Alzheimer’s disease. It can cause side effects that include headaches, constipation, confusion, and dizziness.

A cholinesterase inhibitor combined with a glutamate regulator, such as donepezil and memantine, treats moderate-to-severe Alzheimer’s disease. Possible side effects can include nausea, vomiting, loss of appetite, confusion, dizziness, increased frequency of bowel movements, and constipation.

Alzheimer’s disease doesn’t just impact memory and thinking. It also impacts a person’s quality of life by affecting a variety of behavioral and psychological symptoms that come with dementia, such as agitation, hallucinations and delusions, and sleep disturbances. Some medications focus on treating these non-cognitive symptoms for a time; however, it is important to try non-drug strategies to manage behaviors before adding medications.

The FDA has approved only one drug to manage symptoms of insomnia that has been tested in people who are living with dementia, and one that treats agitation.

Orexin receptor antagonists are prescribed to address symptoms of insomnia and inhibit the activity of a type of neurotransmitter involved in the sleep-wake cycle called orexin.

Suvorexant treats insomnia and has been shown in clinical trials to be effective for people who are living with mild to moderate Alzheimer’s disease. Possible side effects can include a risk of impaired alertness and motor function, worsening depression or suicidal thinking, complex sleep behaviors, sleep paralysis, and compromised respiratory function.

Atypical antipsychotics are a group of antipsychotic drugs that target the serotonin and dopamine chemical pathways in the brain. These drugs are mainly used to treat schizophrenia and bipolar disorder, as well as add-on therapies for major depressive disorder. The FDA requires that all atypical antipsychotics carry a safety warning that the medication has been associated with an increased risk of death in older patients who are experiencing dementia related psychosis.

Many atypical antipsychotic medications are used “off-label” to treat dementia-related behaviors, and there is only one FDA-approved atypical antipsychotic to treat agitation associated with dementia due to Alzheimer’s disease. It is important to try non-drug strategies to help manage non-cognitive symptoms such as agitation before adding any medications.

Brexpiprazole treats agitation associated with dementia due to Alzheimer’s disease. Possible side effects may include weight gain, sleepiness, common cold symptoms, dizziness, and restlessness.

If you or a loved one is experiencing any symptoms of Alzheimer’s disease or would like to learn more about treatment options, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.

Botox for Migraines

Posted on March 14, 2026 by Patrick Hercules

Chronic migraines are a severe, recurring type of headache that is often debilitating. Migraines have four phases, which are prodrome, aura, migraine headache, and postdrome.

Although the exact cause of migraines is unknown, researchers believe genetics is a factor.

There are a few conditions and lifestyle factors that can trigger a migraine, including:

Anxiety

Bipolar disorder

Depression

Epilepsy

Sleep disorders

Caffeine or withdrawal from caffeine

Taking certain medications or taking them too often

Migraines are more likely to occur in the morning, making it common to wake up with a migraine. Some people have a predictable pattern of migraines, such as just before a menstrual period. Other people may have trouble recognizing what triggers their migraines.

There is no cure for migraines, but they can be managed and prevented with over-the-counter triptans and pain relievers.

Another treatment that can be used for chronic migraines is Botox. Botox for migraines is a type of botulinum toxin that may prevent chronic migraines and is only recommended by a healthcare provider if a person has 15 or more headaches per month.

Although Botox is mostly known for its cosmetic use, it has medical benefits, such as blocking pain signals before they reach the brain, as certain nerves are highly active during a migraine.

To prevent this from happening, a healthcare provider injects Botox into specific muscles in the head, neck, and shoulders using a tiny needle. These areas connect to the nerves that send pain signals during a migraine. Botox travels along these connected nerves towards the brainstem and blocks the release of chemicals that trigger pain. This may reduce how often a person gets a migraine or make their symptoms less severe when they experience one.

Before receiving Botox for migraine treatment, you will meet with your healthcare provider, who will explain the risks and benefits of it and make sure that it is a safe option for you. If you agree to move forward, you will sign a consent form.

It is important to let your healthcare provider know about any medications and supplements that you are currently taking, as Botox may interact with different types, such as muscle relaxants.

Botox has many side effects, including:

Mild pain and bruising at the injection site

Neck pain and stiffness

Headache

Flu-like symptoms

Temporary changes in appearance

These side effects are usually minimal and will clear up. Let your healthcare provider know if you are experiencing any severe pain or discomfort.

The main benefits of Botox for migraines are that it reduces:

The severity of migraines

The frequency of migraines

The duration of migraines

Botox for migraines has other benefits, including:

It’s effective with long-term use and has minimal complications

It can be combined with other migraine medications

The side effects may be better tolerated than other medications available

Chronic migraines can be painful and debilitating, and trying to find the right treatment to provide relief can be difficult and frustrating. If you are suffering from chronic migraines and haven’t found the right treatment options to relieve your symptoms, discuss Botox treatment for migraines with your healthcare provider.

If you are experiencing any symptoms of chronic migraines and are interested in Botox for migraines, you can consult with a neurologist at Jamaica Hospital Medical Center. To schedule an appointment, please call (718) 206-7246.